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The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors


Journal article


S. P. Alexander, A. P. Davenport, E. Kelly, Alasdair J Gibb, A. Mathie, Chloe J. Peach, E. Veale, J. Armstrong, E. Faccenda, S. Harding, C. Southan, J. Davies, M. Abbracchio, George R. Abraham, Alexander I. Agoulnik, Wayne Alexander, K. Al‐Hosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross A. D. Bathgate, Jean‐Martin Beaulieu, Annette G. Beck-Sickinger, Maik Behrens, K. Bennett, Kenneth E. Bernstein, B. Bettler, Nigel J. M. Birdsall, V. Blaho, P. Bonaventure, Franc¸ois Boulay, Corinne Bousquet, Hans Bräuner-Osborne, Andrew J. Brown, G. Burnstock, Marta Busnelli, Girolamo Calo', Vanni Caruso, Justo P. Castaño, K. J. Catt, S. Ceruti, P. Chazot, Chia Nan, B. Chini, A. Christopoulos, Jerold Chun, A. Cianciulli, Olivier Civelli, L. Clapp, Réjean Couture, Helen M. Cox, Z. Csaba, Claes Dahlgren, F. Dautzenberg, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Margarita L. Dubocovich, Satoru Eguchi, Emanuel Escher, E. Filardo, Tung M. Fong, H. Forsman, M. Fumagalli, R. Gainetdinov, Michael L. Garelja, Marc Gasparo, Florence Gbahou, C. Gerard, M. Gershengorn, Michelle Glass, David E. Gloriam, Fernand Junior Gobeil, T. Goodfriend, C. Goudet, Lukas Grätz, K. Gregory, Christian J. Gruber, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Deborah S. Hartman, R. Hauger, Deborah L. Hay, A. Heinemann, L. Heitman, D. Herr, M. Hollenberg, Nicholas D. Holliday, Birgitte Holst, M. Horiuchi, D. Hoyer, László Hunyady, Ahsan Husain, A. P. Ijzerman, Tadashi Inagami, Paul A. Insel, K. Jacobson, Laura H. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, K. Kaupmann, Jacqueline R. Kemp, Charles Kennedy, Yasuyuki Kihara, Julia Kinsolving, Takio Kitazawa, Paweł Kozielewicz, H. Kreienkamp, J. Kukkonen, Luxmichan Laishram, Tobias Langenhan, C. Langmead, Dan Larhammar, K. Leach, D. Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, R. Leurs, Xaria X. Li, Ines Liebscher, S. Lolait, Amelie Lupp, Robyn G. C. Macrae, Janet J. Maguire, D. Malfacini, Maurice Manning, Davide Marangon, Kirill A. Martemyanov, Jean Mazella, C. McArdle, S. Melmed, Martin C. Michel, Laurence J. Miller, V. Mitolo, Bernard Mouillac, Christa E. Müller, P. Murphy, J. Nahon, R. Neubig, Tony Ngo, Xavier Norel, Duuamene Nyimanu, A. O'Carroll, S. Offermanns, M. Panaro, M. Parmentier, Nicole A. Perry-Hauser, R. Pertwee, Jean-Philippe Pin, E. Prossnitz, Helena Chengxue Qin, Mark Quinn, S. Raffaele, R. Ramachandran, Manisha Ray, R. Reinscheid, Alejandro Romeral Buzón, P. Rondard, M. Rosenkilde, G. Rovati, C. Ruzza, Gareth J. Sanger, N. Scholz, Torsten Schöneberg, G. Schulte, Stefan Schulz, Deborah Segaloff, Charles N. Serhan, Arun K. Shukla, K. D. Singh, Craig M. Smith, Nicola J Smith, C. Stäubert, Leigh A. Stoddart, Yukihiko Sugimoto, Roger J. Summers, Valerie P. Tan, D. Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan C. Tirupula, L. Toll, G. Tulipano, Hamiyet Unal, T. Unger, C. Valant, P. Vanderheyden, D. Vaudry, H. Vaudry, Joseph G. Verbalis, J. Vilardaga, Christopher Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, G. Willars, T. Williams, Trent M. Woodruff, Huixian Wu, Cheng Yang, Chengcan Yao, Richard D. Ye, Nathan A. Zaidman
British Journal of Pharmacology, 2025

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APA   Click to copy
Alexander, S. P., Davenport, A. P., Kelly, E., Gibb, A. J., Mathie, A., Peach, C. J., … Zaidman, N. A. (2025). The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors. British Journal of Pharmacology.


Chicago/Turabian   Click to copy
Alexander, S. P., A. P. Davenport, E. Kelly, Alasdair J Gibb, A. Mathie, Chloe J. Peach, E. Veale, et al. “The Concise Guide to PHARMACOLOGY 2025/26: G Protein-Coupled Receptors.” British Journal of Pharmacology (2025).


MLA   Click to copy
Alexander, S. P., et al. “The Concise Guide to PHARMACOLOGY 2025/26: G Protein-Coupled Receptors.” British Journal of Pharmacology, 2025.


BibTeX   Click to copy

@article{s2025a,
  title = {The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors},
  year = {2025},
  journal = {British Journal of Pharmacology},
  author = {Alexander, S. P. and Davenport, A. P. and Kelly, E. and Gibb, Alasdair J and Mathie, A. and Peach, Chloe J. and Veale, E. and Armstrong, J. and Faccenda, E. and Harding, S. and Southan, C. and Davies, J. and Abbracchio, M. and Abraham, George R. and Agoulnik, Alexander I. and Alexander, Wayne and Al‐Hosaini, K. and Bäck, Magnus and Baker, Jillian G. and Barnes, Nicholas M. and Bathgate, Ross A. D. and Beaulieu, Jean‐Martin and Beck-Sickinger, Annette G. and Behrens, Maik and Bennett, K. and Bernstein, Kenneth E. and Bettler, B. and Birdsall, Nigel J. M. and Blaho, V. and Bonaventure, P. and Boulay, Franc¸ois and Bousquet, Corinne and Bräuner-Osborne, Hans and Brown, Andrew J. and Burnstock, G. and Busnelli, Marta and Calo', Girolamo and Caruso, Vanni and Castaño, Justo P. and Catt, K. J. and Ceruti, S. and Chazot, P. and Nan, Chia and Chini, B. and Christopoulos, A. and Chun, Jerold and Cianciulli, A. and Civelli, Olivier and Clapp, L. and Couture, Réjean and Cox, Helen M. and Csaba, Z. and Dahlgren, Claes and Dautzenberg, F. and Dent, Gordon and Douglas, Steven D. and Dournaud, Pascal and Dubocovich, Margarita L. and Eguchi, Satoru and Escher, Emanuel and Filardo, E. and Fong, Tung M. and Forsman, H. and Fumagalli, M. and Gainetdinov, R. and Garelja, Michael L. and Gasparo, Marc and Gbahou, Florence and Gerard, C. and Gershengorn, M. and Glass, Michelle and Gloriam, David E. and Gobeil, Fernand Junior and Goodfriend, T. and Goudet, C. and Grätz, Lukas and Gregory, K. and Gruber, Christian J. and Gundlach, Andrew L. and Hamann, Jörg and Hanson, Julien and Hartman, Deborah S. and Hauger, R. and Hay, Deborah L. and Heinemann, A. and Heitman, L. and Herr, D. and Hollenberg, M. and Holliday, Nicholas D. and Holst, Birgitte and Horiuchi, M. and Hoyer, D. and Hunyady, László and Husain, Ahsan and Ijzerman, A. P. and Inagami, Tadashi and Insel, Paul A. and Jacobson, K. and Jacobson, Laura H. and Jensen, Robert T. and Jockers, Ralf and Jonnalagadda, Deepa and Karnik, Sadashiva and Kaupmann, K. and Kemp, Jacqueline R. and Kennedy, Charles and Kihara, Yasuyuki and Kinsolving, Julia and Kitazawa, Takio and Kozielewicz, Paweł and Kreienkamp, H. and Kukkonen, J. and Laishram, Luxmichan and Langenhan, Tobias and Langmead, C. and Larhammar, Dan and Leach, K. and Lecca, D. and Lee, John D. and Leeman, Susan E. and Leprince, Jérôme and Leurs, R. and Li, Xaria X. and Liebscher, Ines and Lolait, S. and Lupp, Amelie and Macrae, Robyn G. C. and Maguire, Janet J. and Malfacini, D. and Manning, Maurice and Marangon, Davide and Martemyanov, Kirill A. and Mazella, Jean and McArdle, C. and Melmed, S. and Michel, Martin C. and Miller, Laurence J. and Mitolo, V. and Mouillac, Bernard and Müller, Christa E. and Murphy, P. and Nahon, J. and Neubig, R. and Ngo, Tony and Norel, Xavier and Nyimanu, Duuamene and O'Carroll, A. and Offermanns, S. and Panaro, M. and Parmentier, M. and Perry-Hauser, Nicole A. and Pertwee, R. and Pin, Jean-Philippe and Prossnitz, E. and Qin, Helena Chengxue and Quinn, Mark and Raffaele, S. and Ramachandran, R. and Ray, Manisha and Reinscheid, R. and Buzón, Alejandro Romeral and Rondard, P. and Rosenkilde, M. and Rovati, G. and Ruzza, C. and Sanger, Gareth J. and Scholz, N. and Schöneberg, Torsten and Schulte, G. and Schulz, Stefan and Segaloff, Deborah and Serhan, Charles N. and Shukla, Arun K. and Singh, K. D. and Smith, Craig M. and Smith, Nicola J and Stäubert, C. and Stoddart, Leigh A. and Sugimoto, Yukihiko and Summers, Roger J. and Tan, Valerie P. and Thal, D. and Thomas, Walter ( Wally) and Timmermans, Pieter B. M. W. M. and Tirupula, Kalyan C. and Toll, L. and Tulipano, G. and Unal, Hamiyet and Unger, T. and Valant, C. and Vanderheyden, P. and Vaudry, D. and Vaudry, H. and Verbalis, Joseph G. and Vilardaga, J. and Walker, Christopher and Wang, Ji Ming and Ward, Donald T. and Wester, Hans‐Jürgen and Willars, G. and Williams, T. and Woodruff, Trent M. and Wu, Huixian and Yang, Cheng and Yao, Chengcan and Ye, Richard D. and Zaidman, Nathan A.}
}

Abstract

The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear, accessible, and well‐structured, rather than the scope of the content, which spans approximately 500 pages. The Concise Guide summarises the key pharmacological properties of around 1900 human drug targets, and nearly 7000 interactions, involving around 4400 ligands. While the content is a substantially condensed version of the more detailed information and links available at the www.guidetopharmacology.org website, the printed guide serves as a permanent, citable, point‐in‐time record, that remains stable despite ongoing updates to the online database. The full contents of this publication can be found at https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70230 .


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